4GAJ

Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 411-424)

4GAJ の概要

• エントリーDOI: 10.2210/pdb4gaj/pdb
• 関連するPDBエントリー: 4GAG 4GAY
• 分子名称: NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN, Genome polyprotein, ... (4 entities in total)
• 機能のキーワード: antibody fab, neutralizing antibody, hcv e2 binding, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49266.64

構造登録者

Potter, J.A.,Owsianka, A.,Taylor, G.L.,Patel, A.H. (登録日: 2012-07-25, 公開日: 2012-10-10, 最終更新日: 2018-01-24)

• 主引用文献: Potter, J.A.,Owsianka, A.M.,Jeffery, N.,Matthews, D.J.,Keck, Z.Y.,Lau, P.,Foung, S.K.,Taylor, G.L.,Patel, A.H.; Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody.; J.Virol., 86:12923-12932, 2012; PubMed: 22993159; DOI: 10.1128/JVI.02052-12

実験手法

X-RAY DIFFRACTION (2.51 Å)