4G6F

Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide

Summary for 4G6F

Entry DOI	10.2210/pdb4g6f/pdb
Descriptor	10E8 Heavy Chain, 10E8 Light Chain, gp41 MPER Peptide, ... (4 entities in total)
Functional Keywords	immunoglobulin, mper, antibody, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	106130.40
Authors	Ofek, G.,Huang, J.,Connors, M.,Kwong, P.D. (deposition date: 2012-07-19, release date: 2012-09-26, Last modification date: 2017-11-15)
Primary citation	Huang, J.,Ofek, G.,Laub, L.,Louder, M.K.,Doria-Rose, N.A.,Longo, N.S.,Imamichi, H.,Bailer, R.T.,Chakrabarti, B.,Sharma, S.K.,Alam, S.M.,Wang, T.,Yang, Y.,Zhang, B.,Migueles, S.A.,Wyatt, R.,Haynes, B.F.,Kwong, P.D.,Mascola, J.R.,Connors, M. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature, 491:406-412, 2012 Cited by PubMed: 23151583 DOI: 10.1038/nature11544 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation