4G59

Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma

Summary for 4G59

Entry DOI	10.2210/pdb4g59/pdb
Descriptor	Retinoic acid early-inducible protein 1-gamma, M152 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	mhc-i fold, immunoevasion, stress induced ligand, immune system
Biological source	Mus musculus (mouse) More
Cellular location	Cell membrane; Lipid-anchor, GPI-anchor: O08604
Total number of polymer chains	4
Total formula weight	120729.28
Authors	Wang, R.,Natarajan, K.,Margulies, D.H. (deposition date: 2012-07-17, release date: 2012-12-19, Last modification date: 2023-09-13)
Primary citation	Wang, R.,Natarajan, K.,Revilleza, M.J.,Boyd, L.F.,Zhi, L.,Zhao, H.,Robinson, H.,Margulies, D.H. Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion. Proc.Natl.Acad.Sci.USA, 109:E3578-E3587, 2012 Cited by PubMed: 23169621 DOI: 10.1073/pnas.1214088109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.44 Å)

Structure validation