4G1W

Crystal structure of JNK1 in complex with JIP1 peptide and 7-Fluoro-3-[4-(2-hydroxy-ethanesulfonyl)-benzyl]-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

4G1W の概要

• エントリーDOI: 10.2210/pdb4g1w/pdb
• 分子名称: Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1, methyl 7-fluoro-3-{4-[(2-hydroxyethyl)sulfonyl]benzyl}-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxylate, ... (4 entities in total)
• 機能のキーワード: kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm (By similarity): Q9UQF2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44429.32

構造登録者

Kuglstatter, A.,Shao, A. (登録日: 2012-07-11, 公開日: 2013-07-17, 最終更新日: 2023-09-13)

• 主引用文献: Gong, L.,Tan, Y.-C.,Boice, G.,Abbot, S.; Crystal structure of JNK1 in complex with JIP1 peptide and inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.45 Å)