4FYG

Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase

4FYG の概要

• エントリーDOI: 10.2210/pdb4fyg/pdb
• 関連するPDBエントリー: 4FYE 4FYF
• 分子名称: SidF, inhibitor of growth family, member 3, (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate (3 entities in total)
• 機能のキーワード: mixed alpha-beta, phosphoinositide phosphatase, phosphoinositides, membrane, hydrolase
• 由来する生物種: Legionella pneumophila subsp. pneumophila
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 86825.71

構造登録者

Hsu, F.S.,Zhu, W.,Brennan, L.,Tao, L.,Luo, Z.Q.,Mao, Y. (登録日: 2012-07-04, 公開日: 2012-08-22, 最終更新日: 2023-09-13)

• 主引用文献: Hsu, F.,Zhu, W.,Brennan, L.,Tao, L.,Luo, Z.Q.,Mao, Y.; Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase.; Proc.Natl.Acad.Sci.USA, 109:13567-13572, 2012; PubMed: 22872863; DOI: 10.1073/pnas.1207903109

実験手法

X-RAY DIFFRACTION (2.822 Å)