4FVT
Human SIRT3 bound to Ac-ACS peptide and Carba-NAD
Summary for 4FVT
Entry DOI | 10.2210/pdb4fvt/pdb |
Related | 4G1C |
Descriptor | NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Acetylated ACS2 peptide, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (7 entities in total) |
Functional Keywords | sirtuin, carba-nad, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion matrix: Q9NTG7 |
Total number of polymer chains | 2 |
Total formula weight | 32206.05 |
Authors | |
Primary citation | Szczepankiewicz, B.G.,Dai, H.,Koppetsch, K.J.,Qian, D.,Jiang, F.,Mao, C.,Perni, R.B. Synthesis of Carba-NAD and the Structures of Its Ternary Complexes with SIRT3 and SIRT5. J.Org.Chem., 77:7319-7329, 2012 Cited by PubMed: 22849721DOI: 10.1021/jo301067e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.47 Å) |
Structure validation
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