4FTX

Crystal structure of Ego3 homodimer

Summary for 4FTX

• Entry DOI: 10.2210/pdb4ftx/pdb
• Related: 4FUW
• Descriptor: Protein SLM4, SUCCINIC ACID (3 entities in total)
• Functional Keywords: ego complex, ego3, tor signaling, protein binding
• Biological source: Saccharomyces cerevisiae (Baker's yeast)
• Cellular location: Vacuole membrane; Single-pass membrane protein: P38247
• Total number of polymer chains: 2
• Total formula weight: 39004.15

Authors

Zhang, T.,Peli-Gulli, M.P.,Yang, H.,De Virgilio, C.,Ding, J. (deposition date: 2012-06-28, release date: 2012-11-28, Last modification date: 2024-03-20)

• Primary citation: Zhang, T.,Peli-Gulli, M.P.,Yang, H.,De Virgilio, C.,Ding, J.; Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.; Structure, 20:2151-2160, 2012; PubMed: 23123112; DOI: 10.1016/j.str.2012.09.019

Experimental method

X-RAY DIFFRACTION (2.1 Å)