4FRO

Crystal Structure of BBBB+UDP+Gal at pH 9.0 with MPD as the cryoprotectant

4FRO の概要

• エントリーDOI: 10.2210/pdb4fro/pdb
• 関連するPDBエントリー: 4FQW 4FRA 4FRB 4FRD 4FRE 4FRH 4FRL 4FRM 4FRP 4FRQ
• 分子名称: Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, GLYCINE, ... (6 entities in total)
• 機能のキーワード: manganese, abo rossmann fold, retaining glycosyltransferase, glycoprotein, blood group antigen, metal-binding, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34852.71

構造登録者

Johal, A.R.,Alfaro, J.A.,Blackler, R.J.,Schuman, B.,Borisova, S.N.,Evans, S.V. (登録日: 2012-06-26, 公開日: 2013-12-25, 最終更新日: 2023-09-13)

• 主引用文献: Johal, A.R.,Blackler, R.J.,Alfaro, J.A.,Schuman, B.,Borisova, S.,Evans, S.V.; pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state.; Glycobiology, 24:237-246, 2014; PubMed: 24265507; DOI: 10.1093/glycob/cwt098

実験手法

X-RAY DIFFRACTION (1.75 Å)