4FNO

Crystal structure of peptidyl t-RNA hydrolase from Pseudomonas aeruginosa at 2.2 Angstrom resolution

Summary for 4FNO

• Entry DOI: 10.2210/pdb4fno/pdb
• Related: 4ERX
• Descriptor: Peptidyl-tRNA hydrolase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... (4 entities in total)
• Functional Keywords: hydrolase
• Biological source: Pseudomonas aeruginosa
• Cellular location: Cytoplasm : Q9HVC3
• Total number of polymer chains: 2
• Total formula weight: 42338.30

Authors

Singh, A.,Kumar, A.,Arora, A.,Singh, N.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2012-06-20, release date: 2012-07-04, Last modification date: 2023-11-08)

• Primary citation: Singh, A.,Kumar, A.,Gautam, L.,Sharma, P.,Sinha, M.,Bhushan, A.,Kaur, P.,Sharma, S.,Arora, A.,Singh, T.P.; Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase; Biochem.J., 463:329-337, 2014; PubMed: 25101795; DOI: 10.1042/BJ20140631

Experimental method

X-RAY DIFFRACTION (2.25 Å)