Crystal structure of the Mtb enoyl CoA isomerase (Rv0632c) in complex with hydroxybutyrl CoA

Summary for 4FNB

Related4FN7 4FN8 4FND
DescriptorEnoyl-CoA hydratase/isomerase family protein, SULFATE ION, 3-HYDROXYBUTANOYL-COENZYME A, ... (4 entities in total)
Functional Keywordsstructural genomics, tb structural genomics consortium, tbsgc, crotonase superfamily, isomerase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total molecular weight25608.76
Primary citation
Bruning, J.B.,Gao, N.,Hernandez, E.D.,Li, H.,Dang, N.,Hung, L.W.,Moran, S.,Sacchettini, J.C.
Crystal Structure and Mechanism of the Prokaryotic Enoyl CoA Isomerase
To be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.213400.6%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution