4FN2

Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ37

4FN2 の概要

• エントリーDOI: 10.2210/pdb4fn2/pdb
• 関連するPDBエントリー: 2KEO 2KO7 2L2S 3UF8 3UQA 3UQB 3VAW 4DZ2 4DZ3
• 分子名称: Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase, ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate (3 entities in total)
• 機能のキーワード: ssgcid, structural genomics, seattle structural genomics center for infectious disease, isomerase, protein binding
• 由来する生物種: Saccharomyces cerevisiae; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46510.38

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-06-19, 公開日: 2012-08-01, 最終更新日: 2023-09-13)

• 主引用文献: Begley, D.W.,Fox, D.,Jenner, D.,Juli, C.,Pierce, P.G.,Abendroth, J.,Muruthi, M.,Safford, K.,Anderson, V.,Atkins, K.,Barnes, S.R.,Moen, S.O.,Raymond, A.C.,Stacy, R.,Myler, P.J.,Staker, B.L.,Harmer, N.J.,Norville, I.H.,Holzgrabe, U.,Sarkar-Tyson, M.,Edwards, T.E.,Lorimer, D.D.; A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.; Antimicrob.Agents Chemother., 58:1458-1467, 2014; PubMed: 24366729; DOI: 10.1128/AAC.01875-13

実験手法

X-RAY DIFFRACTION (1.95 Å)