4FJ1
Crystal Structure of the ternary complex between a fungal 17beta-hydroxysteroid dehydrogenase (Holo form) and genistein
Summary for 4FJ1
Entry DOI | 10.2210/pdb4fj1/pdb |
Related | 3IS3 3ITD 3QWF 3QWH 3QWI 4FIZ 4FJ0 4FJ2 |
Descriptor | 17beta-hydroxysteroid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | short chain dehydrogenase/reductase, rossmann fold, oxidoreductase, nadp(h), oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Cochliobolus lunatus (Filamentous fungus) |
Total number of polymer chains | 4 |
Total formula weight | 120197.87 |
Authors | Cassetta, A.,Lamba, D.,Krastanova, I. (deposition date: 2012-06-11, release date: 2013-07-03, Last modification date: 2023-09-13) |
Primary citation | Cassetta, A.,Stojan, J.,Krastanova, I.,Kristan, K.,Brunskole Svegelj, M.,Lamba, D.,Rizner, T.L. Structural basis for inhibition of 17 beta-hydroxysteroid dehydrogenases by phytoestrogens: The case of fungal 17 beta-HSDcl. J. Steroid Biochem. Mol. Biol., 171:80-93, 2017 Cited by PubMed: 28259640DOI: 10.1016/j.jsbmb.2017.02.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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