4FIV
FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130
Summary for 4FIV
| Entry DOI | 10.2210/pdb4fiv/pdb |
| Descriptor | FELINE IMMUNODEFICIENCY VIRUS PROTEASE, 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE (3 entities in total) |
| Functional Keywords | aspartic protease, fiv, retropepsin, retrovirus, cat |
| Biological source | Feline immunodeficiency virus |
| Total number of polymer chains | 1 |
| Total formula weight | 13637.80 |
| Authors | Kervinen, J.,Lubkowski, J.,Zdanov, A.,Wlodawer, A.,Gustchina, A. (deposition date: 1998-07-15, release date: 1999-01-13, Last modification date: 2023-08-09) |
| Primary citation | Kervinen, J.,Lubkowski, J.,Zdanov, A.,Bhatt, D.,Dunn, B.M.,Hui, K.Y.,Powell, D.J.,Kay, J.,Wlodawer, A.,Gustchina, A. Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7:2314-2323, 1998 Cited by PubMed: 9827997PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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