4FEL

Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine

Summary for 4FEL

Entry DOI	10.2210/pdb4fel/pdb
Related	1U8D 4FE5 4FEJ 4FEN 4FEO 4FEP
Descriptor	U25A/A46G mutant of the B. subtilis xpt-pbuX guanine riboswitch aptamer domain, HYPOXANTHINE, ACETATE ION, ... (5 entities in total)
Functional Keywords	three-way junction with distal tertiary interaction, genetic regulatory element, hypoxanthine, rna
Total number of polymer chains	1
Total formula weight	23191.02
Authors	Stoddard, C.D.,Trausch, J.J.,Widmann, J.,Marcano, J.,Knight, R.,Batey, R.T. (deposition date: 2012-05-30, release date: 2013-02-27, Last modification date: 2024-02-28)
Primary citation	Stoddard, C.D.,Widmann, J.,Trausch, J.J.,Marcano-Velazquez, J.G.,Knight, R.,Batey, R.T. Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425:1596-1611, 2013 Cited by PubMed: 23485418 DOI: 10.1016/j.jmb.2013.02.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation