4F5K
Substrate Specificity Conversion of Aspartate Aminotransferase to Tyrosine Aminotransferase By The JANUS Algorithm: Chimera P6.
Summary for 4F5K
Entry DOI | 10.2210/pdb4f5k/pdb |
Related | 4F5F 4F5G 4F5H 4F5I 4F5J 4F5L 4F5M |
Descriptor | Aspartate aminotransferase (2 entities in total) |
Functional Keywords | aminotransferase, transferase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P00509 |
Total number of polymer chains | 2 |
Total formula weight | 89620.85 |
Authors | Addington, T.A.,Fisher, A.J.,Toney, M.D. (deposition date: 2012-05-13, release date: 2013-02-13, Last modification date: 2013-04-24) |
Primary citation | Addington, T.A.,Mertz, R.W.,Siegel, J.B.,Thompson, J.M.,Fisher, A.J.,Filkov, V.,Fleischman, N.M.,Suen, A.A.,Zhang, C.,Toney, M.D. Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425:1378-1389, 2013 Cited by PubMed: 23396064DOI: 10.1016/j.jmb.2013.01.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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