4F3T

Human Argonaute-2 - miR-20a complex

Summary for 4F3T

• Entry DOI: 10.2210/pdb4f3t/pdb
• Descriptor: Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3'), PHENOL, ... (4 entities in total)
• Functional Keywords: hydrolase/gene regulation, rnai, slicer, rna, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, P-body : Q9UKV8
• Total number of polymer chains: 2
• Total formula weight: 104115.39

Authors

Elkayam, E.,Kuhn, C.-D.,Tocilj, A.,Joshua-Tor, L. (deposition date: 2012-05-09, release date: 2012-05-30, Last modification date: 2024-02-28)

• Primary citation: Elkayam, E.,Kuhn, C.D.,Tocilj, A.,Haase, A.D.,Greene, E.M.,Hannon, G.J.,Joshua-Tor, L.; The Structure of Human Argonaute-2 in Complex with miR-20a.; Cell(Cambridge,Mass.), 150:100-110, 2012; PubMed: 22682761; DOI: 10.1016/j.cell.2012.05.017

Experimental method

X-RAY DIFFRACTION (2.25 Å)