4F3C
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A
4F3C の概要
エントリーDOI | 10.2210/pdb4f3c/pdb |
関連するPDBエントリー | 4F1W 4F2P 4F2W 4F3K |
分子名称 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, 1,2-ETHANEDIOL, ... (4 entities in total) |
機能のキーワード | l-methionine biosynthetic process from s-adenosylmethionine, l-methionine salvage from methylthioadenosine, 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase, adenosylhomocysteine nucleosidase activity, methylthioadenosine nucleosidase activity, acting on glycosyl bonds, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Salmonella enterica subsp. enterica serovar Choleraesuis |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 53505.29 |
構造登録者 | Haapalainen, A.M.,Thomas, K.,Bonanno, J.B.,Almo, S.C.,Schramm, V.L. (登録日: 2012-05-09, 公開日: 2013-05-01, 最終更新日: 2024-02-28) |
主引用文献 | Haapalainen, A.M.,Thomas, K.,Tyler, P.C.,Evans, G.B.,Almo, S.C.,Schramm, V.L. Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A Structure, 21:963-974, 2013 Cited by PubMed: 23685211DOI: 10.1016/j.str.2013.04.009 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.93 Å) |
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