4F2V

Crystal Structure of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR165

4F2V の概要

• エントリーDOI: 10.2210/pdb4f2v/pdb
• 関連するPDBエントリー: 1BQ2
• 分子名称: De novo designed serine hydrolase, DODECYL-ALPHA-D-MALTOSIDE, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• 機能のキーワード: structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg, de novo design, de novo protein
• 由来する生物種: artificial gene
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64376.74

構造登録者

Kuzin, A.,Lew, S.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Rajagopalan, S.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (登録日: 2012-05-08, 公開日: 2012-05-30, 最終更新日: 2023-12-06)

• 主引用文献: Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D.; Design of activated serine-containing catalytic triads with atomic-level accuracy.; Nat.Chem.Biol., 10:386-391, 2014; PubMed: 24705591; DOI: 10.1038/nchembio.1498

実験手法

X-RAY DIFFRACTION (2.493 Å)