4F2B

Modulation of S.Aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding

Summary for 4F2B

Entry DOI	10.2210/pdb4f2b/pdb
Related	3V16 3V18 3V1H 4F2T 4F2U
Descriptor	1-phosphatidylinositol phosphodiesterase, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE (3 entities in total)
Functional Keywords	dimer, phosphatidylinositol-specific phospholipase c, lyase
Biological source	Staphylococcus aureus subsp. aureus
Cellular location	Secreted: P45723
Total number of polymer chains	2
Total formula weight	70844.59
Authors	Cheng, J.,Goldstein, R.,Stec, B.,Gershenson, A.,Roberts, M.F. (deposition date: 2012-05-07, release date: 2012-12-12, Last modification date: 2023-09-13)
Primary citation	Cheng, J.,Goldstein, R.,Stec, B.,Gershenson, A.,Roberts, M.F. Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity. J.Biol.Chem., 287:40317-40327, 2012 Cited by PubMed: 23038258 DOI: 10.1074/jbc.M112.395277 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation