4EY8

Crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2

4EY8 の概要

• エントリーDOI: 10.2210/pdb4ey8/pdb
• 分子名称: Acetylcholinesterase, Fasciculin-2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: acetylcholinesterase, hydrolase, fasciculin 2, snake venom toxin, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 67554.02

構造登録者

Cheung, J.,Rudolph, M.,Burshteyn, F.,Cassidy, M.,Gary, E.,Love, J.,Height, J.,Franklin, M. (登録日: 2012-05-01, 公開日: 2012-10-17, 最終更新日: 2023-09-13)

• 主引用文献: Cheung, J.,Rudolph, M.J.,Burshteyn, F.,Cassidy, M.S.,Gary, E.N.,Love, J.,Franklin, M.C.,Height, J.J.; Structures of human acetylcholinesterase in complex with pharmacologically important ligands.; J.Med.Chem., 55:10282-10286, 2012; PubMed: 23035744; DOI: 10.1021/jm300871x

実験手法

X-RAY DIFFRACTION (2.5958 Å)