4EXN

Crystal structure of mouse Interleukin-34

Summary for 4EXN

• Entry DOI: 10.2210/pdb4exn/pdb
• Related: 4EXP
• Descriptor: Interleukin-34, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: extended 4-helix bundle, c-fms, csf-1r, cytokine
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 4
• Total formula weight: 87612.57

Authors

Liu, H.,Leo, C.,Chen, X.,Wong, B.R.,Williams, L.T.,Lin, H.,He, X. (deposition date: 2012-04-30, release date: 2012-05-30, Last modification date: 2020-07-29)

• Primary citation: Liu, H.,Leo, C.,Chen, X.,Wong, B.R.,Williams, L.T.,Lin, H.,He, X.; The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.; Biochim.Biophys.Acta, 1824:938-945, 2012; PubMed: 22579672; DOI: 10.1016/j.bbapap.2012.04.012

Experimental method

X-RAY DIFFRACTION (2.7 Å)