4EXN

Crystal structure of mouse Interleukin-34

4EXN の概要

• エントリーDOI: 10.2210/pdb4exn/pdb
• 関連するPDBエントリー: 4EXP
• 分子名称: Interleukin-34, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: extended 4-helix bundle, c-fms, csf-1r, cytokine
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 87612.57

構造登録者

Liu, H.,Leo, C.,Chen, X.,Wong, B.R.,Williams, L.T.,Lin, H.,He, X. (登録日: 2012-04-30, 公開日: 2012-05-30, 最終更新日: 2020-07-29)

• 主引用文献: Liu, H.,Leo, C.,Chen, X.,Wong, B.R.,Williams, L.T.,Lin, H.,He, X.; The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.; Biochim.Biophys.Acta, 1824:938-945, 2012; PubMed: 22579672; DOI: 10.1016/j.bbapap.2012.04.012

実験手法

X-RAY DIFFRACTION (2.7 Å)