4EXH
The crystal structure of xmrv protease complexed with acetyl-pepstatin
Summary for 4EXH
| Entry DOI | 10.2210/pdb4exh/pdb |
| Related | 3SM1 |
| Related PRD ID | PRD_001057 |
| Descriptor | Putative gag-pro-pol polyprotein, ACETYL-PEPSTATIN, FORMIC ACID, ... (4 entities in total) |
| Functional Keywords | beta sheet, dimer, protease, acetyl-pepstain, virus, hydrolase-hydrol inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | DG-75 Murine leukemia virus More |
| Cellular location | Virion : Q9E7M1 |
| Total number of polymer chains | 5 |
| Total formula weight | 30620.04 |
| Authors | Li, M.,Wlodawer, A. (deposition date: 2012-04-30, release date: 2012-08-01, Last modification date: 2017-11-15) |
| Primary citation | Matuz, K.,Motyan, J.,Li, M.,Wlodawer, A. Inhibition of XMRV and HIV-1 proteases by pepstatin A and acetyl-pepstatin. Febs J., 279:3276-3286, 2012 Cited by PubMed: 22804908DOI: 10.1111/j.1742-4658.2012.08714.x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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