4ERA

Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase

Summary for 4ERA

• Entry DOI: 10.2210/pdb4era/pdb
• Related: 4EPK 4ERG 4ERI
• Descriptor: 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, COBALT (II) ION (3 entities in total)
• Functional Keywords: tim-barrel, decarboxylase, metal-binding, co(ii), lyase
• Biological source: Pseudomonas fluorescens
• Total number of polymer chains: 2
• Total formula weight: 74535.11

Authors

Huo, L.,Fielding, A.J.,Chen, Y.,Li, T.,Iwaki, H.,Hosler, J.P.,Chen, L.,Hasegawa, Y.,Que Jr., L.,Liu, A. (deposition date: 2012-04-19, release date: 2012-08-22, Last modification date: 2023-09-13)

• Primary citation: Huo, L.,Fielding, A.J.,Chen, Y.,Li, T.,Iwaki, H.,Hosler, J.P.,Chen, L.,Hasegawa, Y.,Que, L.,Liu, A.; Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase; Biochemistry, 51:5811-5821, 2012; PubMed: 22746257; DOI: 10.1021/bi300635b

Experimental method

X-RAY DIFFRACTION (2.398 Å)