4EJI

Human Cytochrome P450 2A13 in complex with two molecules of 4-(methylnitrosamino)-1-(3-puridyl)-1-butanone

4EJI の概要

• エントリーDOI: 10.2210/pdb4eji/pdb
• 関連するPDBエントリー: 2P85 3T3S 4EJG 4EJH 4EJJ
• 分子名称: Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE, 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one, ... (4 entities in total)
• 機能のキーワード: cyp2a13, cytochrome p450 2a13, p450 2a13, heme protein, monooxygenase, drug metabolism, xenobiotic metabolism, endoplasmic reticulum, membrane, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein: Q16696
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55835.70

構造登録者

DeVore, N.M.,Scott, E.E. (登録日: 2012-04-06, 公開日: 2012-06-06, 最終更新日: 2023-09-13)

• 主引用文献: DeVore, N.M.,Scott, E.E.; Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes.; J.Biol.Chem., 287:26576-26585, 2012; PubMed: 22700965; DOI: 10.1074/jbc.M112.372813

実験手法

X-RAY DIFFRACTION (2.1 Å)