4EJ4

Structure of the delta opioid receptor bound to naltrindole

4EJ4 の概要

• エントリーDOI: 10.2210/pdb4ej4/pdb
• 分子名称: Delta-type opioid receptor, Lysozyme chimera, (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol (2 entities in total)
• 機能のキーワード: g-protein coupled receptor, 7 transmembrane receptor, opioid receptor, signaling protein, hydrolase-antagonist complex, hydrolase/antagonist
• 由来する生物種: Mus musculus; 詳細
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : P32300
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52048.23

構造登録者

Granier, S.,Manglik, A.,Kruse, A.C.,Kobilka, T.S.,Thian, F.S.,Weis, W.I.,Kobilka, B.K. (登録日: 2012-04-06, 公開日: 2012-05-16, 最終更新日: 2023-09-13)

• 主引用文献: Granier, S.,Manglik, A.,Kruse, A.C.,Kobilka, T.S.,Thian, F.S.,Weis, W.I.,Kobilka, B.K.; Structure of the delta opioid receptor bound to naltrindole; Nature, 485:400-404, 2012; PubMed: 22596164; DOI: 10.1038/nature11111

実験手法

X-RAY DIFFRACTION (3.4 Å)