4EEO

Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-GlcNAc-ALPHA-benzyl

4EEO の概要

• エントリーDOI: 10.2210/pdb4eeo/pdb
• 関連するPDBエントリー: 4EE3 4EE4 4EE5 4EEA 4EEG 4EEM
• 分子名称: Beta-1,4-galactosyltransferase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-benzyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: gt-a fold, glycosyltansferase, udp-galacotse, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 102573.53

構造登録者

Ramakrishnan, B.,Qasba, P.K. (登録日: 2012-03-28, 公開日: 2012-07-04, 最終更新日: 2023-09-13)

• 主引用文献: Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K.; Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.; J.Biol.Chem., 287:28666-28674, 2012; PubMed: 22740701; DOI: 10.1074/jbc.M112.373514

実験手法

X-RAY DIFFRACTION (2.3 Å)