4E3F

Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors

4E3F の概要

• エントリーDOI: 10.2210/pdb4e3f/pdb
• 関連するPDBエントリー: 4E3D 4E3G 4E3H 4E49 4E4A
• 分子名称: Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (5 entities in total)
• 機能のキーワード: carbonate dehydratase, inhibitor binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : P00918
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30138.53

構造登録者

Cohen, S.M.,Martin, D.P. (登録日: 2012-03-09, 公開日: 2012-06-27, 最終更新日: 2023-11-08)

• 主引用文献: Martin, D.P.,Cohen, S.M.; Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors; Chem.Commun.(Camb.), 48:5259-5261, 2012; PubMed: 22531842; DOI: 10.1039/c2cc32013d

実験手法

X-RAY DIFFRACTION (1.5 Å)