4DXL
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abscessus, bound to CMP and ATP
Summary for 4DXL
Entry DOI | 10.2210/pdb4dxl/pdb |
Descriptor | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | ssgcid, nih, niaid, sbri, emerald biostructures, structural genomics, seattle structural genomics center for infectious disease, transferase |
Biological source | Mycobacterium abscessus |
Total number of polymer chains | 1 |
Total formula weight | 33608.41 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-02-27, release date: 2012-03-07, Last modification date: 2023-09-13) |
Primary citation | Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J. Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95:142-148, 2015 Cited by PubMed: 25613812DOI: 10.1016/j.tube.2014.12.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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