4DVY

Crystal structure of the Helicobacter pylori CagA oncoprotein

Summary for 4DVY

Entry DOI	10.2210/pdb4dvy/pdb
Related	4DVZ
Descriptor	Cytotoxicity-associated immunodominant antigen (1 entity in total)
Functional Keywords	oncoprotein
Biological source	Helicobacter pylori
Total number of polymer chains	1
Total formula weight	98442.99
Authors	Hayashi, T.,Senda, M.,Morohashi, H.,Higashi, H.,Horio, M.,Kashiba, Y.,Nagase, L.,Sasaya, D.,Shimizu, T.,Venugopalan, N.,Kumeta, H.,Noda, N.,Inagaki, F.,Senda, T.,Hatakeyama, M. (deposition date: 2012-02-23, release date: 2012-07-25, Last modification date: 2023-11-08)
Primary citation	Hayashi, T.,Senda, M.,Morohashi, H.,Higashi, H.,Horio, M.,Kashiba, Y.,Nagase, L.,Sasaya, D.,Shimizu, T.,Venugopalan, N.,Kumeta, H.,Noda, N.N.,Inagaki, F.,Senda, T.,Hatakeyama, M. Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA Cell Host Microbe, 12:20-33, 2012 Cited by PubMed: 22817985 DOI: 10.1016/j.chom.2012.05.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation