4DTB

Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type IVa in Complex with Guanosine

Summary for 4DTB

• Entry DOI: 10.2210/pdb4dtb/pdb
• Related: 4DT8 4DT9 4DTA
• Descriptor: APH(2'')-Id, GUANOSINE, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: aminoglycoside kinase, transferase
• Biological source: Enterococcus casseliflavus
• Total number of polymer chains: 2
• Total formula weight: 73627.04

Authors

Shi, K.,Berghuis, A.M. (deposition date: 2012-02-20, release date: 2012-03-07, Last modification date: 2024-02-28)

• Primary citation: Shi, K.,Berghuis, A.M.; Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2''-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases.; J.Biol.Chem., 287:13094-13102, 2012; PubMed: 22371504; DOI: 10.1074/jbc.M112.349670

Experimental method

X-RAY DIFFRACTION (2.1 Å)