4DMU

Crystal structure of the von Willebrand factor A3 domain in complex with a collagen III derived triple-helical peptide

Summary for 4DMU

• Entry DOI: 10.2210/pdb4dmu/pdb
• Related: 4DMT
• Descriptor: Collagen III derived triple-helical peptide, von Willebrand factor, SULFATE ION (3 entities in total)
• Functional Keywords: dinucleotide binding fold, collagen binding, platelet activation, hemostasis, plasma, structural protein-protein binding complex, structural protein/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P04275
• Total number of polymer chains: 12
• Total formula weight: 169102.55

Authors

Brondijk, T.H.C.,Huizinga, E.G. (deposition date: 2012-02-08, release date: 2012-03-28, Last modification date: 2023-09-13)

• Primary citation: Brondijk, T.H.,Bihan, D.,Farndale, R.W.,Huizinga, E.G.; Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex.; Proc.Natl.Acad.Sci.USA, 109:5253-5258, 2012; PubMed: 22440751; DOI: 10.1073/pnas.1112388109

Experimental method

X-RAY DIFFRACTION (2.8 Å)