4DLP

Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis bound to selenomethionine

4DLP の概要

• エントリーDOI: 10.2210/pdb4dlp/pdb
• 関連するPDBエントリー: 3SP1 3TZE
• 分子名称: Aminoacyl-tRNA synthetase, class I:Aminoacyl-tRNA synthetase, class Ia:Methionyl-tRNA synthetase, class Ia, SELENOMETHIONINE (3 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, class ia aminoacyl-trna synthetase, selenomethionine, anomalous signal, protein synthesis, atp-dependent, ligase
• 由来する生物種: Brucella melitensis biovar Abortus 2308
• 細胞内の位置: Cytoplasm : Q2YQ76
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 181601.62

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-02-06, 公開日: 2012-02-15, 最終更新日: 2023-12-06)

• 主引用文献: Ojo, K.K.,Ranade, R.M.,Zhang, Z.,Dranow, D.M.,Myers, J.B.,Choi, R.,Nakazawa Hewitt, S.,Edwards, T.E.,Davies, D.R.,Lorimer, D.,Boyle, S.M.,Barrett, L.K.,Buckner, F.S.,Fan, E.,Van Voorhis, W.C.; Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.; Plos One, 11:e0160350-e0160350, 2016; PubMed: 27500735; DOI: 10.1371/journal.pone.0160350

実験手法

X-RAY DIFFRACTION (2.65 Å)