4DKY

Crystal structure Analysis of N terminal region containing the dimerization domain and DNA binding domain of HU protein(Histone like protein-DNA binding) from Mycobacterium tuberculosis [H37Ra]

4DKY の概要

• エントリーDOI: 10.2210/pdb4dky/pdb
• 関連するPDBエントリー: 3C4I
• 分子名称: DNA-binding protein HU homolog, MANGANESE (II) ION (3 entities in total)
• 機能のキーワード: nucleoid associated protein, nucleoid architecture, histone-like, hu, hu-ihf fold, genome compaction, gene regulation, dna binding protein
• 由来する生物種: Mycobacterium tuberculosis H37Ra
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23306.30

構造登録者

Bhowmick, T.,Ramagopal, U.A.,Ghosh, S.,Nagaraja, V.,Ramakumar, S. (登録日: 2012-02-05, 公開日: 2013-02-06, 最終更新日: 2023-11-08)

• 主引用文献: Bhowmick, T.,Ghosh, S.,Dixit, K.,Ganesan, V.,Ramagopal, U.A.,Dey, D.,Sarma, S.P.,Ramakumar, S.,Nagaraja, V.; Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors; Nat Commun, 5:4124-4124, 2014; PubMed: 24916461; DOI: 10.1038/ncomms5124

実験手法

X-RAY DIFFRACTION (2.478 Å)