4DJS
Structure of beta-catenin in complex with a stapled peptide inhibitor
Summary for 4DJS
| Entry DOI | 10.2210/pdb4djs/pdb |
| Descriptor | Catenin beta-1, stapled peptide RRWPQ(MK8)ILD(MK8)HVRRVWR (2 entities in total) |
| Functional Keywords | transcription regulation, signaling protein-inhibitor complex, signaling protein/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 58832.40 |
| Authors | Bowman, B.R.,Grossmann, T.N.,Yeh, J.T.-H.,Verdine, G.L. (deposition date: 2012-02-02, release date: 2012-10-17, Last modification date: 2019-07-17) |
| Primary citation | Grossmann, T.N.,Yeh, J.T.,Bowman, B.R.,Chu, Q.,Moellering, R.E.,Verdine, G.L. Inhibition of oncogenic Wnt signaling through direct targeting of beta-catenin. Proc.Natl.Acad.Sci.USA, 109:17942-17947, 2012 Cited by PubMed: 23071338DOI: 10.1073/pnas.1208396109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.029 Å) |
Structure validation
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