4DJH
Structure of the human kappa opioid receptor in complex with JDTic
4DJH の概要
エントリーDOI | 10.2210/pdb4djh/pdb |
分子名称 | Kappa-type opioid receptor, Lysozyme, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CITRIC ACID, ... (6 entities in total) |
機能のキーワード | jdtic, gpcr newtork, psi-biology, kor, hkor, kop, structural genomics, protein structure initiative, gpcr network, g-protein coupled receptor, gpcr, 7tm, kappa opioid receptor, dynorphin, membrane protein, transmembrane, hormone receptor, hydrolase, hormone receptor-antagonist complex, hormone receptor/antagonist |
由来する生物種 | Homo Sapiens (human, Bacteriophage T4) 詳細 |
細胞内の位置 | Cell membrane ; Multi-pass membrane protein : P41145 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 110629.66 |
構造登録者 | Wu, H.,Wacker, D.,Katritch, V.,Mileni, M.,Han, G.W.,Vardy, E.,Liu, W.,Thompson, A.A.,Huang, X.P.,Carroll, F.I.,Mascarella, S.W.,Westkaemper, R.B.,Mosier, P.D.,Roth, B.L.,Cherezov, V.,Stevens, R.C.,GPCR Network (GPCR) (登録日: 2012-02-01, 公開日: 2012-03-21, 最終更新日: 2023-09-13) |
主引用文献 | Wu, H.,Wacker, D.,Mileni, M.,Katritch, V.,Han, G.W.,Vardy, E.,Liu, W.,Thompson, A.A.,Huang, X.P.,Carroll, F.I.,Mascarella, S.W.,Westkaemper, R.B.,Mosier, P.D.,Roth, B.L.,Cherezov, V.,Stevens, R.C. tructure of the human kappa-opioid receptor in complex with JDTic Nature, 485:327-332, 2012 Cited by PubMed: 22437504DOI: 10.1038/nature10939 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.9 Å) |
構造検証レポート
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