4DG2

Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20

4DG2 の概要

• エントリーDOI: 10.2210/pdb4dg2/pdb
• 関連するPDBエントリー: 1ATP 1CTP 1JBP 4DFX 4DFZ 4DG0
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MYRISTIC ACID, ... (4 entities in total)
• 機能のキーワード: protein kinase, myristoylated, phosphotransferase of ser/thr, mg, pki, pka regulatory subunits, phosphorylated on s139, t197, s338, myristoylated on g1, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm: P05132
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43165.05

構造登録者

Bastidas, A.C.,Steichen, J.M.,Taylor, S.S. (登録日: 2012-01-24, 公開日: 2012-06-06, 最終更新日: 2013-01-02)

• 主引用文献: Bastidas, A.C.,Deal, M.S.,Steichen, J.M.,Keshwani, M.M.,Guo, Y.,Taylor, S.S.; Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.; J.Mol.Biol., 422:215-229, 2012; PubMed: 22617327; DOI: 10.1016/j.jmb.2012.05.021

実験手法

X-RAY DIFFRACTION (2 Å)