4DFH

Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain

Summary for 4DFH

• Entry DOI: 10.2210/pdb4dfh/pdb
• Related: 4DFI
• Descriptor: Poliovirus receptor-related protein 2 (2 entities in total)
• Functional Keywords: cell adhesion, dnam-1, cell surface
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein: Q92692
• Total number of polymer chains: 2
• Total formula weight: 27901.56

Authors

Liu, J.,Qian, X.,Chen, Z.,Xu, X.,Gao, F.,Zhang, S.,Zhang, R.,Qi, J.,Gao, G.F.,Yan, J. (deposition date: 2012-01-23, release date: 2012-06-06)

• Primary citation: Liu, J.,Qian, X.,Chen, Z.,Xu, X.,Gao, F.,Zhang, S.,Zhang, R.,Qi, J.,Gao, G.F.,Yan, J.; Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226; J.Immunol., 188:5511-5520, 2012; PubMed: 22547693; DOI: 10.4049/jimmunol.1200324

Experimental method

X-RAY DIFFRACTION (1.85 Å)