4DCQ
Crystal Structure of the Fab Fragment of 3B5H10, an Antibody-Specific for Extended Polyglutamine Repeats (orthorhombic form)
Summary for 4DCQ
Entry DOI | 10.2210/pdb4dcq/pdb |
Related | 3S96 |
Descriptor | 3B5H10 FAB Light Chain, 3B5H10 FAB Heavy Chain, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | fab fragment, immunoglobulin domain, anti-polyglutamine, polyglutamine repeats, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 47223.02 |
Authors | Peters-Libeu, C.A.,Tran, T.,Finkbeiner, S.,Weisgraber, K. (deposition date: 2012-01-18, release date: 2012-02-22, Last modification date: 2023-09-13) |
Primary citation | Peters-Libeu, C.,Miller, J.,Rutenber, E.,Newhouse, Y.,Krishnan, P.,Cheung, K.,Hatters, D.,Brooks, E.,Widjaja, K.,Tran, T.,Mitra, S.,Arrasate, M.,Mosquera, L.A.,Taylor, D.,Weisgraber, K.H.,Finkbeiner, S. Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. J.Mol.Biol., 421:587-600, 2012 Cited by PubMed: 22306738DOI: 10.1016/j.jmb.2012.01.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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