4DCG

VACCINIA METHYLTRANSFERASE VP39 MUTANT D182A COMPLEXED WITH M7G AND S-ADENOSYLHOMOCYSTEINE

Summary for 4DCG

DescriptorVP39, S-ADENOSYL-L-HOMOCYSTEINE, 7-METHYLGUANOSINE, ... (4 entities in total)
Functional Keywordsmethylated guanosine, methyltransferase mutant d182a, rna cap analog, poly(a) polymerase, vaccinia, mrna processing, transcription, complex (transferase-rna cap analog)
Biological sourceVaccinia virus
Total number of polymer chains1
Total molecular weight36560.11
Authors
Hu, G.,Hodel, A.E.,Gershon, P.D.,Quiocho, F.A. (deposition date: 1998-07-13, release date: 1999-07-22, Last modification date: 2011-07-13)
Primary citation
Hu, G.,Gershon, P.D.,Hodel, A.E.,Quiocho, F.A.
mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96:7149-7154, 1999
PubMed: 10377383 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.96.13.7149
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers706.0%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution