4DBM

Aplysia californica-AChBP in complex with triazole 18

4DBM の概要

• エントリーDOI: 10.2210/pdb4dbm/pdb
• 関連するPDBエントリー: 2BYN
• 分子名称: Soluble acetylcholine receptor, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: in situ click-chemistry, achbp, nicotinic, triazole, tropane, quinolinone, cys-loop receptor homologue, acetylcholine-binding protein
• 由来する生物種: Aplysia californica (California sea hare)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 134165.01

構造登録者

Nemecz, A.,Yamauchi, J.G.,Kim, C. (登録日: 2012-01-16, 公開日: 2012-03-21, 最終更新日: 2023-09-13)

• 主引用文献: Grimster, N.P.,Stump, B.,Fotsing, J.R.,Weide, T.,Talley, T.T.,Yamauchi, J.G.,Nemecz, A.,Kim, C.,Ho, K.Y.,Sharpless, K.B.,Taylor, P.,Fokin, V.V.; Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template.; J.Am.Chem.Soc., 134:6732-6740, 2012; PubMed: 22394239; DOI: 10.1021/ja3001858

実験手法

X-RAY DIFFRACTION (2.3 Å)