4DAW
Crystal structure of PAK1 kinase domain with the ruthenium phthalimide complex
Summary for 4DAW
Entry DOI | 10.2210/pdb4daw/pdb |
Descriptor | Serine/threonine-protein kinase PAK 1, [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium (3 entities in total) |
Functional Keywords | serine/threonine kinase, phosphorylation, atp-binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q13153 |
Total number of polymer chains | 1 |
Total formula weight | 33929.96 |
Authors | Maksimoska, J.,Marmorstein, R. (deposition date: 2012-01-13, release date: 2012-03-14, Last modification date: 2023-09-13) |
Primary citation | Blanck, S.,Maksimoska, J.,Baumeister, J.,Harms, K.,Marmorstein, R.,Meggers, E. The art of filling protein pockets efficiently with octahedral metal complexes. Angew.Chem.Int.Ed.Engl., 51:5244-5246, 2012 Cited by PubMed: 22383326DOI: 10.1002/anie.201108865 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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