4D3I

Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 6,6'-((5-(aminomethyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis(4- methylpyridin-2-amine)

Summary for 4D3I

• Entry DOI: 10.2210/pdb4d3i/pdb
• Related: 4D3J 4D3K 4D3M 4D3N 4D3O
• Descriptor: NITRIC OXIDE SYNTHASE OXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, 6,6'-{[5-(aminomethyl)benzene-1,3-diyl]diethane-2,1-diyl}bis(4-methylpyridin-2-amine), ... (6 entities in total)
• Functional Keywords: nitric oxide synthase, oxidoreductase, inhibitor
• Biological source: BACILLUS SUBTILIS
• Total number of polymer chains: 1
• Total formula weight: 42991.36

Authors

Holden, J.K.,Poulos, T.L. (deposition date: 2014-10-22, release date: 2015-01-14, Last modification date: 2023-12-20)

• Primary citation: Holden, J.K.,Kang, S.,Hollingsworth, S.A.,Li, H.,Lim, N.,Chen, S.,Huang, H.,Xue, F.,Tang, W.,Silverman, R.B.,Poulos, T.L.; Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors.; J.Med.Chem., 58:994-, 2015; PubMed: 25522110; DOI: 10.1021/JM501723P

Experimental method

X-RAY DIFFRACTION (2.09 Å)