4CP5
ndpK in complex with (Rp)-SPMPApp
Summary for 4CP5
| Entry DOI | 10.2210/pdb4cp5/pdb |
| Descriptor | NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC, [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-sulfanyl-phosphoryl] phosphono hydrogen phosphate (3 entities in total) |
| Functional Keywords | transferase |
| Biological source | DICTYOSTELIUM DISCOIDEUM |
| Total number of polymer chains | 6 |
| Total formula weight | 103190.88 |
| Authors | Priet, S.,Ferron, F.,Alvarez, K.,Verron, M.,Canard, B. (deposition date: 2014-01-31, release date: 2015-02-11, Last modification date: 2023-12-20) |
| Primary citation | Priet, S.,Roux, L.,Saez-Ayala, M.,Ferron, F.,Canard, B.,Alvarez, K. Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity. Antiviral Res., 117:122-, 2015 Cited by PubMed: 25766862DOI: 10.1016/J.ANTIVIRAL.2015.03.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
Download full validation report
