4CN4

GlgE isoform 1 from Streptomyces coelicolor E423A mutant with 2-deoxy- 2-fluoro-beta-maltosyl modification

Summary for 4CN4

Entry DOI	10.2210/pdb4cn4/pdb
Related	4CN1 4CN6
Descriptor	ALPHA-1,4-GLUCAN\:MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-beta-D-glucopyranose (3 entities in total)
Functional Keywords	transferase, alpha-glucan biosynthesis, glycoside hydrolase family 13_3, drug target
Biological source	STREPTOMYCES COELICOLOR
Total number of polymer chains	2
Total formula weight	155702.20
Authors	Syson, K.,Stevenson, C.E.M.,Rashid, A.M.,Saalbach, G.,Tang, M.,Tuukanen, A.,Svergun, D.I.,Withers, S.G.,Lawson, D.M.,Bornemann, S. (deposition date: 2014-01-21, release date: 2014-05-21, Last modification date: 2023-12-20)
Primary citation	Syson, K.,Stevenson, C.E.M.,Rashid, A.M.,Saalbach, G.,Tang, M.,Tuukkanen, A.,Svergun, D.I.,Withers, S.G.,Lawson, D.M.,Bornemann, S. Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate. Biochemistry, 53:2494-, 2014 Cited by PubMed: 24689960 DOI: 10.1021/BI500183C PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation