4CEY
Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor NLD
Summary for 4CEY
| Entry DOI | 10.2210/pdb4cey/pdb |
| Related | 4CDQ 4CDU 4CDW 4CDX 4CEW |
| Descriptor | VP1, VP2, VP3, ... (7 entities in total) |
| Functional Keywords | virus, hand-foot-and-mouth disease, enterovirus uncoating, inhibitor |
| Biological source | ENTEROVIRUS A71 More |
| Cellular location | Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): B2ZUN0 B2ZUN0 B2ZUN0 B2ZUN0 |
| Total number of polymer chains | 4 |
| Total formula weight | 94880.82 |
| Authors | De Colibus, L.,Wang, X.,Spyrou, J.A.B.,Kelly, J.,Ren, J.,Grimes, J.,Puerstinger, G.,Stonehouse, N.,Walter, T.S.,Hu, Z.,Wang, J.,Li, X.,Peng, W.,Rowlands, D.,Fry, E.E.,Rao, Z.,Stuart, D.I. (deposition date: 2013-11-12, release date: 2014-02-12, Last modification date: 2014-03-19) |
| Primary citation | De Colibus, L.,Wang, X.,Spyrou, J.A.B.,Kelly, J.,Ren, J.,Grimes, J.,Puerstinger, G.,Stonehouse, N.,Walter, T.S.,Hu, Z.,Wang, J.,Li, X.,Peng, W.,Rowlands, D.J.,Fry, E.E.,Rao, Z.,Stuart, D.I. More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules Nat.Struct.Mol.Biol., 21:282-, 2014 Cited by PubMed: 24509833DOI: 10.1038/NSMB.2769 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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