4CCE

STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX

4CCE の概要

• エントリーDOI: 10.2210/pdb4cce/pdb
• 関連するPDBエントリー: 4CCC 4CCD
• 分子名称: GALACTOCEREBROSIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose, ... (6 entities in total)
• 機能のキーワード: hydrolase, krabbe disease, glycosyl hydrolase, lysosomal storage disease, enzyme-product complex
• 由来する生物種: MUS MUSCULUS (HOUSE MOUSE)
• 細胞内の位置: Lysosome (By similarity): P54818
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 76311.39

構造登録者

Hill, C.H.,Graham, S.C.,Read, R.J.,Deane, J.E. (登録日: 2013-10-21, 公開日: 2013-12-11, 最終更新日: 2023-12-20)

• 主引用文献: Hill, C.H.,Graham, S.C.,Read, R.J.,Deane, J.E.; Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease; Proc.Natl.Acad.Sci.USA, 110:20479-, 2013; PubMed: 24297913; DOI: 10.1073/PNAS.1311990110

実験手法

X-RAY DIFFRACTION (2.06 Å)