4CBO

Crystal structure of Complement Factor D mutant R202A after ensemble refinement

Summary for 4CBO

• Entry DOI: 10.2210/pdb4cbo/pdb
• Related: 4CBN
• Descriptor: COMPLEMENT FACTOR D, GLYCEROL (3 entities in total)
• Functional Keywords: hydrolase, factor d, ensemble refinement
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P00746
• Total number of polymer chains: 2
• Total formula weight: 48889.57

Authors

Forneris, F.,Burnley, B.T.,Gros, P. (deposition date: 2013-10-15, release date: 2013-12-18, Last modification date: 2023-12-20)

• Primary citation: Forneris, F.,Burnley, B.T.,Gros, P.; Ensemble Refinement Shows Conformational Flexibility in Crystal Structures of Human Complement Factor D; Acta Crystallogr.,Sect.D, 70:733-, 2014; PubMed: 24598742; DOI: 10.1107/S1399004713032549

Experimental method

X-RAY DIFFRACTION (1.8 Å)