4CBO

Crystal structure of Complement Factor D mutant R202A after ensemble refinement

Summary for 4CBO

Related4CBN
DescriptorCOMPLEMENT FACTOR D, GLYCEROL (3 entities in total)
Functional Keywordshydrolase, factor d, ensemble refinement
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P00746
Total number of polymer chains2
Total molecular weight48889.57
Authors
Forneris, F.,Burnley, B.T.,Gros, P. (deposition date: 2013-10-15, release date: 2013-12-18, Last modification date: 2016-01-27)
Primary citation
Forneris, F.,Burnley, B.T.,Gros, P.
Ensemble Refinement Shows Conformational Flexibility in Crystal Structures of Human Complement Factor D
Acta Crystallogr.,Sect.D, 70:733-, 2014
PubMed: 24598742 (PDB entries with the same primary citation)
DOI: 10.1107/S1399004713032549
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
?

Structure validation

RfreeRamachandran outliersSidechain outliersRSRZ outliers0.2325.8%12.0%15.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution