4C6F

Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.5

Summary for 4C6F

Related4C6B 4C6C 4C6D 4C6E 4C6I
DescriptorDIHYDROOROTASE, (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, N-CARBAMOYL-L-ASPARTATE, ... (6 entities in total)
Functional Keywordshydrolase, amidohydrolase superfamily, metalloenzyme, zinc binding, histidinate anion
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P27708
Total number of polymer chains1
Total molecular weight43696
Authors
Ramon-Maiques, S.,Lallous, N.,Grande-Garcia, A. (deposition date: 2013-09-18, release date: 2014-02-05, Last modification date: 2014-02-19)
Primary citation
Grande-Garcia, A.,Lallous, N.,Diaz-Tejada, C.,Ramon-Maiques, S.
Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22:185-, 2014
PubMed: 24332717 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2013.10.016
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.261 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.13330.8%1.7%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report