4C51

Crystal Structure of the Catalase-Peroxidase (KatG) R418L mutant from Mycobacterium Tuberculosis

Summary for 4C51

Related4C50
DescriptorCATALASE-PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, ALPHA-D-GLUCOSE, ... (4 entities in total)
Functional Keywordsoxidoreductase
Biological sourceMYCOBACTERIUM TUBERCULOSIS H37RV
Total number of polymer chains2
Total molecular weight162880.43
Authors
Hersleth, H.-P.,Zhao, X.,Magliozzo, R.S.,Andersson, K.K. (deposition date: 2013-09-10, release date: 2013-11-13, Last modification date: 2013-11-27)
Primary citation
Zhao, X.,Hersleth, H.P.,Zhu, J.,Andersson, K.K.,Magliozzo, R.S.
Access Channel Residues Ser315 and Asp137 in Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) Control Peroxidatic Activation of the Pro-Drug Isoniazid.
Chem.Commun.(Camb.), 49:11650-, 2013
PubMed: 24185282 (PDB entries with the same primary citation)
DOI: 10.1039/C3CC47022A
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21471.1%4.5%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution